Southern Creamy Parmesan Chicken

Featured in: Main Dishes

This Southern-inspired dish features tender chicken seasoned with smoky spices, cooked to golden perfection, then combined with pasta in a velvety Parmesan cream sauce. The luscious, smooth sauce blends heavy cream, butter, and freshly grated Parmesan, enriched with a hint of garlic and lemon juice for brightness. Topped with optional crispy bacon and fresh herbs, this comforting dish comes together quickly, making it ideal for a satisfying weeknight dinner with rich Italian and Southern fusion flavors.

Updated on Sat, 22 Nov 2025 10:34:00 GMT
Golden, sliced Southern Style Creamy Parmesan Chicken Pasta rests on a serving plate, ready to be enjoyed. Save
Golden, sliced Southern Style Creamy Parmesan Chicken Pasta rests on a serving plate, ready to be enjoyed. | cheerfulchefs.com

Tender, Southern-spiced chicken crowns rich, silky parmesan cream sauce tossed with pasta for a true comfort classic with Italian flair ready in just 30 minutes.

I first served this dish to my family on a chilly evening and it quickly became a requested favorite because of its creamy texture and bold flavors

Ingredients

  • Chicken: 1½ lbs boneless, skinless chicken breasts (pounded to ¾-inch thickness), 2 tsp smoked paprika, 1 tsp garlic powder, 1 tsp onion powder, 1 tsp dried thyme, ½ tsp cayenne pepper (adjust to taste), 1 tsp salt, ½ tsp black pepper, 3 tbsp olive oil
  • Pasta: 12 oz fettuccine or penne pasta
  • Sauce: 4 tbsp butter, 4 cloves garlic, minced, ¼ cup all-purpose flour, 2 cups heavy cream, 1 cup whole milk, 1½ cups freshly grated Parmesan cheese, 4 oz cream cheese, softened, 2 tbsp fresh lemon juice, 1 tsp Worcestershire sauce
  • Garnish: 2 strips bacon, cooked and crumbled (optional), 2 green onions, sliced, ¼ cup fresh parsley, chopped, Red pepper flakes (to taste), Fresh cracked black pepper (to taste)

Instructions

Step 1:
Place chicken breasts between sheets of plastic wrap and pound to ¾-inch thickness for even cooking.
Step 2:
In a small bowl, combine paprika, garlic powder, onion powder, thyme, cayenne, salt, and black pepper.
Step 3:
Season both sides of the chicken thoroughly with the spice mixture.
Step 4:
Heat olive oil in a large skillet over medium-high heat. Cook chicken for 67 minutes per side until golden brown and cooked through. Transfer to a plate, let rest 5 minutes, then slice into strips. Reserve skillet drippings.
Step 5:
Meanwhile, bring a large pot of salted water to a boil. Cook pasta according to package instructions until al dente. Reserve 1 cup pasta water, then drain.
Step 6:
In a medium saucepan over medium heat, melt butter. Add minced garlic sauté 1 minute. Whisk in flour and cook 2 minutes stirring constantly to form a light roux.
Step 7:
Gradually whisk in heavy cream and milk. Add Worcestershire sauce. Simmer whisking until slightly thickened (about 34 minutes).
Step 8:
Remove pan from heat. Whisk in cream cheese until fully smooth. Add Parmesan cheese in batches, stirring until melted and sauce is velvety.
Step 9:
Stir in lemon juice. Season with additional salt and pepper to taste. Thin sauce with reserved pasta water as needed for desired consistency.
Step 10:
Toss cooked pasta in the sauce to coat evenly.
Step 11:
Arrange sliced chicken over pasta or mix in. Reheat gently if needed.
Step 12:
Top with bacon (if using), green onions, parsley, red pepper flakes, and extra cracked black pepper. Serve hot with additional Parmesan if desired.
Creamy Parmesan Chicken Pasta showcasing tender chicken atop buttery pasta in a rich, velvety sauce. Save
Creamy Parmesan Chicken Pasta showcasing tender chicken atop buttery pasta in a rich, velvety sauce. | cheerfulchefs.com

This recipe always brings my family together especially on weekend dinners when we share stories and enjoy comfort food

Required Tools

Large skillet, Large pot, Medium saucepan, Meat mallet, Whisk, Tongs, Cheese grater, Colander

Allergen Information

Contains Milk/Dairy (cream, milk, Parmesan, cream cheese, butter), Wheat/Gluten (pasta, flour) Bacon may contain sulfites Individuals with allergies should double-check all ingredient labels

Nutritional Information

Calories 545, Total Fat 30 g, Carbohydrates 39 g, Protein 33 g per serving

A close-up of Southern Style Creamy Parmesan Chicken Pasta with fresh herbs and crumbled bacon is a beautiful sight. Save
A close-up of Southern Style Creamy Parmesan Chicken Pasta with fresh herbs and crumbled bacon is a beautiful sight. | cheerfulchefs.com

Follow these tips for the best creamy chicken pasta experience and enjoy a delightful homestyle meal

Recipe FAQs

How do I keep the chicken tender and juicy?

Pounding the chicken breasts to an even thickness ensures uniform cooking, while letting them rest after cooking preserves juiciness.

Can I adjust the spice level in the seasoning?

Yes, modify the amount of cayenne pepper to suit your preferred heat intensity without compromising the smoky Southern flavor.

What pasta types work best with this creamy sauce?

Fettuccine and penne are ideal as their shapes hold the silky Parmesan cream sauce well, providing a balanced bite.

How do I prevent the sauce from curdling?

Use freshly grated Parmesan and avoid boiling the sauce after adding cheese. Stir gently and keep the sauce at a low simmer.

Is it possible to lighten the sauce?

Substitute half-and-half for heavy cream or Greek yogurt for cream cheese to reduce richness while maintaining creaminess.

Southern Creamy Parmesan Chicken

Tender Southern-spiced chicken crowns with rich Parmesan cream sauce and pasta, perfect for hearty meals.

Prep Time
10 minutes
Cook Time
20 minutes
Overall Time
30 minutes
Creator Ruby Smiles

Recipe Type Main Dishes

Skill Level Medium

Cuisine Background Southern Fusion

Portions 4 Serves

Dietary Preferences None specified

What You’ll Need

Chicken

01 1½ lbs boneless, skinless chicken breasts, pounded to ¾-inch thickness
02 2 tsp smoked paprika
03 1 tsp garlic powder
04 1 tsp onion powder
05 1 tsp dried thyme
06 ½ tsp cayenne pepper, adjust to taste
07 1 tsp salt
08 ½ tsp black pepper
09 3 tbsp olive oil

Pasta

01 12 oz fettuccine or penne pasta

Sauce

01 4 tbsp unsalted butter
02 4 cloves garlic, minced
03 ¼ cup all-purpose flour
04 2 cups heavy cream
05 1 cup whole milk
06 1½ cups freshly grated Parmesan cheese
07 4 oz cream cheese, softened
08 2 tbsp fresh lemon juice
09 1 tsp Worcestershire sauce

Garnish

01 2 strips bacon, cooked and crumbled (optional)
02 2 green onions, sliced
03 ¼ cup fresh parsley, chopped
04 Red pepper flakes, to taste
05 Fresh cracked black pepper, to taste

Step-by-Step Guide

Step 01

Prepare Chicken: Pound chicken breasts between plastic wrap to ¾-inch thickness to ensure even cooking.

Step 02

Season Chicken: Mix paprika, garlic powder, onion powder, thyme, cayenne, salt, and black pepper. Coat chicken evenly on both sides with the spice blend.

Step 03

Cook Chicken: Heat olive oil in a large skillet over medium-high heat. Sear chicken for 6–7 minutes per side until golden and cooked through. Transfer to a plate, let rest 5 minutes, then slice into strips. Reserve skillet drippings.

Step 04

Cook Pasta: Bring a large pot of salted water to a boil. Cook pasta according to package directions until al dente. Reserve 1 cup pasta water, then drain.

Step 05

Make Roux: In a medium saucepan over medium heat, melt butter. Add minced garlic and sauté for 1 minute. Whisk in flour and cook for 2 minutes, stirring constantly to form a light roux.

Step 06

Prepare Sauce: Gradually whisk in heavy cream and whole milk. Stir in Worcestershire sauce and simmer while whisking for 3–4 minutes until slightly thickened.

Step 07

Incorporate Cheeses: Remove from heat. Whisk in cream cheese until smooth, then add Parmesan gradually, stirring until melted and sauce is velvety smooth.

Step 08

Season Sauce: Stir in lemon juice and adjust seasoning with salt and pepper. Thin sauce with reserved pasta water to the preferred consistency.

Step 09

Combine Pasta and Sauce: Toss cooked pasta in the sauce until fully coated.

Step 10

Add Chicken: Arrange sliced chicken over pasta or fold into the sauce. Reheat gently if necessary.

Step 11

Garnish and Serve: Top with optional bacon, green onions, parsley, red pepper flakes, and fresh cracked black pepper. Serve immediately with extra Parmesan if desired.

Tools You’ll Need

  • Large skillet
  • Large pot
  • Medium saucepan
  • Meat mallet
  • Whisk
  • Tongs
  • Cheese grater
  • Colander

Potential Allergens

Inspect ingredients for specific allergens and contact a professional for concerns.
  • Contains dairy (butter, cream, milk, Parmesan, cream cheese) and gluten (pasta, flour).
  • Bacon may contain sulfites.

Nutritional Details (Per Serving)

Provided as supportive info; always cross-check with your healthcare provider.
  • Calories: 545
  • Fats: 30 grams
  • Carbohydrates: 39 grams
  • Proteins: 33 grams